Fourth International Workshop on

Hybrid Systems Biology

Madrid, Spain, September 4-5, 2015
at Madrid Meet 2015

 

Workshop Programme


Friday, September 4th

09:15 - 09:30 Opening

09:30 - 11:30 Session 1: Statistical analysis

   Chair: Nicola Paoletti
09:30 - 10:00
Eugenio Cinquemani (INRIA Grenoble)
Reconstructing statistics of promoter switching from reporter protein population snapshot data
10:00 - 10:30
Adam Streck and Heike Siebert (FU Berlin)
Comparative Statistical Analysis of Qualitative Parametrization Sets
10:30 - 11:30 Coffee Break

11:30 - 13:30 Session 2: Analysis and verification of continuous and hybrid models

   Chair: Luca Bortolussi
11:30 - 12:00
R. Ramanathan, Yan Zhang, Jun Zhou, Weng-Fai Wong and P. S. Thiagarajan (National Univ. of Singapore)
Parallelized Statistical Model Checking for Analysis of Biological Pathways
12:00 - 12:30
Lubos Brim, Martin Demko, Samuel Pastva and David Safranek (MU Brno)
High-Performance Discrete Bifurcation Analysis for Piecewise-Affine Dynamical Systems
12:30 - 13:00
Louis Fippo Fitime, Christian Schuster, Peter Angel, Olivier Roux and Carito Guziolowski (Univ. of Nantes / DKFZ-ZMBH Heidelberg)
Integrating time-series data on large-scale cell-based models
13:00 - 13:30
Benjamin M. Gyori, Bing Liu, Soumya Paul, R Ramanathan and P S Thiagarajan (National Univ. of Singapore / IRIT France / Harvard / Univ. of Pittsburgh)
Approximate Probabilistic Verification of Hybrid Systems
13:30 - 15:00 Lunch Break

15:00 - 16:00 Plenary Talk 1

   Chair: Alessandro Abate
15:00 - 16:00
Invited Speaker: Luca Cardelli (Microsoft Research)
Morphisms of reaction networks
16:00 - 16:30 Coffee Break

16:30 - 18:30 Poster Session


Saturday, September 5th

09:30 - 10:30 Plenary Talk 2

   Chair: David Safranek
09:30 - 10:30
Invited Speaker: Mustafa Khammash (ETH Zurich)
Cybergenetics: Synthetic Circuits and Systems for the Precise Control of Living Cells
10:30 - 11:00 Coffee Break

11:00 - 13:00 Session 3: Quantitative analysis of biological models

   Chair: Milan Ceska
11.00 - 11:30
Marta Kwiatkowska, Alexandru Mereacre, Nicola Paoletti and Andrea Patane' (Univ. of Oxford / Univ. of Catania)
Synthesising robust and optimal parameters for cardiac pacemakers using symbolic and evolutionary computation techniques
11:30 - 12:00
Christoph Bock, Luca Bortolussi, Thilo Krüger and Linar Mikeev (Saarland University / Univ. of Trieste / CeMM Vienna / Max Planck Inst. Saarbrucken)
Model-based whole genome analysis of DNA methylation fidelity
12:00 - 12:30
Laura Nenzi, Ezio Bartocci, Luca Bortolussi, Dimitrios Milios and Guido Sanguinetti (IMT Lucca / TU Vienna / Univ. of Trieste / Saarland Univ. / Univ. of Edinburgh)
Studying Emergent Behaviours in Morphogenesis using Signal Spatio-Temporal Logic
12:30 - 13:00
Andreea Beica, Calin Guet and Tatjana Petrov (IST Vienna)
Efficient reduction of Kappa models by static inspection of the rule-set
13:00 - 14:30 Lunch Break

14:30-16:00 Session 4: Application of advanced models on case studies

   Chair: Tatjana Petrov
14:30 - 15:00
Md. Ariful Islam, Richard Defrancisco, Chuchu Fan, Radu Grosu, Sayan Mitra and Scott Smolka (Stony Brook Univ. / TU Vienna / Univ. of Illiois Urbana Champ.)
Model Checking Tap Withdrawal in C. Elegans
15:00 - 15:30
Delphine Draelants, Przemyslaw Klosiewicz, Jan Broeckhove and Wim Vanroose (Univ. of Antwerp)
Solving General Auxin Transport Models with a Numerical Continuation Toolbox in Python: PyNCT
15:30 - 16:00
Gustavo Santos-Garcia, Javier De Las Rivas and Carolyn Talcott (Univ. of Salamanca / SRI Int.)
Analysis of Cellular Proliferation and Survival Signaling by Using Two Ligand/Receptor Systems Modeled by Pathway Logic
16:00 - 16:30 Coffee Break and Closing