Fourth International Workshop on

Hybrid Systems Biology

Madrid, Spain, September 4-5, 2015
at Madrid Meet 2015



HSB 2015 will be a two-day workshop, co-located with CONCUR 2015, the 26th Conference on Concurrency Theory), QEST 2015 (12th International Conference on Quantitative Evaluation of SysTems), FORMATS 2015 (13th International Conference on Formal Modeling and Analysis of Timed Systems), and among other events as part of the Madrid Meet 2015 meeting.

Plenary Speakers


Systems biology aims at providing a system-level understanding of biological systems by unveiling their structure, dynamics, and control methods. Living systems are intrinsically multi-scale in space and in time; they also exhibit a mixture of deterministic and stochastic behaviours. It is therefore very difficult to model them homogeneously, for example by means of systems of differential equations or by purely discrete models. Furthermore, such models are often not easily amenable to formal analysis and even their simulations are frequently impractical. Indeed, an important open problem is finding appropriate computational models that scale-up well for both simulation and formal analysis of biological processes.

Hybrid modelling techniques, combining discrete and continuous components and dynamics, are gaining more and more attention in systems biology. They have been applied to successfully capture the behaviour of several biological complex systems, including genetic regulatory networks, metabolic reactions, signalling pathways as well as higher level models of tissues and organs. As the challenges of scale and intrinsic heterogeneity and inhomogeneity are coming to the forefront of systems biology, the value of the hybrid dynamical modelling paradigm, integrating mathematical models that address distinct spatio-temporal scales and subsystems, becomes evident.


In this spirit, the scope of the HSB workshop is the general area of dynamical models in Biology with an emphasis on hybrid approaches — by no means restricted to a narrow class of mathematical models — and taking advantage of techniques developed separately in different areas.

Topics of interest include, but are not limited to:

Call for Contributions (TXT)

Submission of full and short papers and posters has been closed. See the list of accepted papers, list of accepted posters, and the workshop programme.


The registration can be done via the Madrid Meet 2015.

Important Dates

  Posters/Demos Submission:  
  August 15, 2015 (closed) 
  Paper Submission:  
  June 19, 2015 (closed) 
  Author Notification:  
  July 17, 2015
  Early Registration:  
  July 24, 2015 
  Final Submission:  
  September 11, 2015

Accepted Papers

Accepted Posters/Demos

Program co-Chairs

Program Committee

Steering Committee

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